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Journal Articles

Bezzi, M. Seitzer, N. Ishikawa, T. Reschke, M. Chen, M. Wang, G. Mitchell, C. Ng, C. Katon, J. Lunardi, A. Signoretti, S. Clohessy, J.G. Zhang, J. Pandolfi, P.P. (2018). Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms. Nature medicine, Vol.24 (2), pp. 165-175.

Mzoughi, S. Zhang, J. Hequet, D. Teo, S.X. Fang, H. Xing, Q.R. Bezzi, M. Seah, M.K. Ong, S.L. Shin, E.M. Wollmann, H. Wong, E.S. Al-Haddawi, M. Stewart, C.L. Tergaonkar, V. Loh, Y.-. Dunn, N.R. Messerschmidt, D.M. Guccione, E. (2017). PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK–ERK signaling. Nature genetics, Vol.49 (9), pp. 1354-1363.

Bezzi, M. Guarnerio, J. Pandolfi, P.P. (2017). A circular twist on microRNA regulation. Cell research, Vol.27 (12), pp. 1401-1402.

Guarnerio, J. Bezzi, M. Jeong, J.C. Paffenholz, S.V. Berry, K. Naldini, M.M. Lo-Coco, F. Tay, Y. Beck, A.H. Pandolfi, P.P. (2016). Oncogenic Role of Fusion-circRNAs Derived from Cancer-Associated Chromosomal Translocations. Cell, Vol.165 (2), pp. 289-302.

Koh, C.M. Bezzi, M. Guccione, E. (2015). The Where and the How of PRMT5. Current molecular biology reports, Vol.1 (1), pp. 19-28.

Koh, C.M. Bezzi, M. Low, D.H. Ang, W.X. Teo, S.X. Gay, F.P. Al-Haddawi, M. Tan, S.Y. Osato, M. Sabò, A. Amati, B. Wee, K.B. Guccione, E. (2015). MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis. Nature, Vol.523 (7558), pp. 96-100.

Dewaele, M. Tabaglio, T. Willekens, K. Bezzi, M. Teo, S.X. Low, D.H. Koh, C.M. Rambow, F. Fiers, M. Rogiers, A. Radaelli, E. Al-Haddawi, M. Tan, S.Y. Hermans, E. Amant, F. Yan, H. Lakshmanan, M. Koumar, R.C. Lim, S.T. Derheimer, F.A. Campbell, R.M. Bonday, Z. Tergaonkar, V. Shackleton, M. Blattner, C. Marine, J.-. Guccione, E. (2015). Antisense oligonucleotide–mediated MDM4 exon 6 skipping impairs tumor growth. Journal of clinical investigation, Vol.126 (1), pp. 68-84.

Qiu, B. Shi, X. Wong, E.T. Lim, J. Bezzi, M. Low, D. Zhou, Q. Akıncılar, S.C. Lakshmanan, M. Swa, H.L. Tham, J.M. Gunaratne, J. Cheng, K.K. Hong, W. Lam, K.S. Ikawa, M. Guccione, E. Xu, A. Han, W. Tergaonkar, V. (2014). NUCKS Is a Positive Transcriptional Regulator of Insulin Signaling. Cell reports, Vol.7 (6), pp. 1876-1886.

Bezzi, M. Teo, S.X. Muller, J. Mok, W.C. Sahu, S.K. Vardy, L.A. Bonday, Z.Q. Guccione, E. (2013). Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery. Genes & development, Vol.27 (17), pp. 1903-1916.  show abstract

Migliori, V. Müller, J. Phalke, S. Low, D. Bezzi, M. Mok, W.C. Sahu, S.K. Gunaratne, J. Capasso, P. Bassi, C. Cecatiello, V. De Marco, A. Blackstock, W. Kuznetsov, V. Amati, B. Mapelli, M. Guccione, E. (2012). Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance. Nature structural & molecular biology, Vol.19 (2), pp. 136-144.

Phalke, S. Mzoughi, S. Bezzi, M. Jennifer, N. Mok, W.C. Low, D.H. Thike, A.A. Kuznetsov, V.A. Tan, P.H. Voorhoeve, P.M. Guccione, E. (2012). p53-Independent regulation of p21Waf1/Cip1 expression and senescence by PRMT6. Nucleic acids research, Vol.40 (19), pp. 9534-9542.

Kumpf, S. Mihlan, M. Goginashvili, A. Grandl, G. Gehart, H. Godel, A. Schmidt, J. Müller, J. Bezzi, M. Ittner, A. Guccione, E. Wolfrum, C. Ricci, R. (2012). Hairless promotes PPARγ expression and is required for white adipogenesis. Embo reports, Vol.13 (11), pp. 1012-1020.  show abstract

Migliori, V. Phalke, S. Bezzi, M. Guccione, E. (2010). Arginine/lysine–methyl/methyl switches: biochemical role of histone arginine methylation in transcriptional regulation. Epigenomics, Vol.2 (1), pp. 119-137.  show abstract

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