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Gatenbee, C.D. Baker, A.-. Schenck, R.O. Strobl, M. West, J. Neves, M.P. Hasan, S.Y. Lakatos, E. Martinez, P. Cross, W.C. Jansen, M. Rodriguez-Justo, M. Whelan, C.J. Sottoriva, A. Leedham, S. Robertson-Tessi, M. Graham, T.A. Anderson, A.R. (2022). Immunosuppressive niche engineering at the onset of human colorectal cancer. , Vol.13 (1), p. 1798.  show abstract

Palles, C. West, H.D. Chew, E. Galavotti, S. Flensburg, C. Grolleman, J.E. Jansen, E.A. Curley, H. Chegwidden, L. Arbe-Barnes, E.H. Lander, N. Truscott, R. Pagan, J. Bajel, A. Sherwood, K. Martin, L. Thomas, H. Georgiou, D. Fostira, F. Goldberg, Y. Adams, D.J. van der Biezen, S.A. Christie, M. Clendenning, M. Thomas, L.E. Deltas, C. Dimovski, A.J. Dymerska, D. Lubinski, J. Mahmood, K. van der Post, R.S. Sanders, M. Weitz, J. Taylor, J.C. Turnbull, C. Vreede, L. van Wezel, T. Whalley, C. Arnedo-Pac, C. Caravagna, G. Cross, W. Chubb, D. Frangou, A. Gruber, A.J. Kinnersley, B. Noyvert, B. Church, D. Graham, T. Houlston, R. Lopez-Bigas, N. Sottoriva, A. Wedge, D. Genomics England Research Consortium, CORGI Consortium, WGS500 Consortium, Jenkins, M.A. Kuiper, R.P. Roberts, A.W. Cheadle, J.P. Ligtenberg, M.J. Hoogerbrugge, N. Koelzer, V.H. Rivas, A.D. Winship, I.M. Ponte, C.R. Buchanan, D.D. Power, D.G. Green, A. Tomlinson, I.P. Sampson, J.R. Majewski, I.J. de Voer, R.M. (2022). Germline MBD4 deficiency causes a multi-tumor predisposition syndrome. , Vol.109 (5), pp. 953-960.  show abstract

Reijns, M.A. Parry, D.A. Williams, T.C. Nadeu, F. Hindshaw, R.L. Rios Szwed, D.O. Nicholson, M.D. Carroll, P. Boyle, S. Royo, R. Cornish, A.J. Xiang, H. Ridout, K. Genomics England Research Consortium, Colorectal Cancer Domain UK 100, Schuh, A. Aden, K. Palles, C. Campo, E. Stankovic, T. Taylor, M.S. Jackson, A.P. (2022). Signatures of TOP1 transcription-associated mutagenesis in cancer and germline. Nature, .  show abstract

Heide, T. Househam, J. Cresswell, G.D. Spiteri, I. Lynn, C. Mossner, M. Kimberley, C. Fernandez-Mateos, J. Chen, B. Zapata, L. James, C. Barozzi, I. Chkhaidze, K. Nichol, D. Gunasri, V. Berner, A. Schmidt, M. Lakatos, E. Baker, A.-. Costa, H. Mitchinson, M. Piazza, R. Jansen, M. Caravagna, G. Ramazzotti, D. Shibata, D. Bridgewater, J. Rodriguez-Justo, M. Magnani, L. Graham, T.A. Sottoriva, A. (2022). The co-evolution of the genome and epigenome in colorectal cancer. , .  show abstract

Househam, J. Heide, T. Cresswell, G.D. Spiteri, I. Kimberley, C. Zapata, L. Lynn, C. James, C. Mossner, M. Fernandez-Mateos, J. Vinceti, A. Baker, A.-. Gabbutt, C. Berner, A. Schmidt, M. Chen, B. Lakatos, E. Gunasri, V. Nichol, D. Costa, H. Mitchinson, M. Ramazzotti, D. Werner, B. Iorio, F. Jansen, M. Caravagna, G. Barnes, C.P. Shibata, D. Bridgewater, J. Rodriguez-Justo, M. Magnani, L. Sottoriva, A. Graham, T.A. (2022). Phenotypic plasticity and genetic control in colorectal cancer evolution. , .  show abstract

Tari, H. Kessler, K. Trahearn, N. Werner, B. Vinci, M. Jones, C. Sottoriva, A. (2022). Quantification of spatial subclonal interactions enhancing the invasive phenotype of pediatric glioma. , Vol.40 (9), p. 111283.  show abstract

Stankunaite, R. George, S.L. Gallagher, L. Jamal, S. Shaikh, R. Yuan, L. Hughes, D. Proszek, P.Z. Carter, P. Pietka, G. Heide, T. James, C. Tari, H. Lynn, C. Jain, N. Portela, L.R. Rogers, T. Vaidya, S.J. Chisholm, J.C. Carceller, F. Szychot, E. Mandeville, H. Angelini, P. Jesudason, A.B. Jackson, M. Marshall, L.V. Gatz, S.A. Anderson, J. Sottoriva, A. Chesler, L. Hubank, M. (2021). Circulating tumour DNA sequencing to determine therapeutic response and identify tumour heterogeneity in patients with paediatric solid tumours. European journal of cancer (oxford, england : 1990), .  show abstract

Caravagna, G. Heide, T. Williams, M.J. Zapata, L. Nichol, D. Chkhaidze, K. Cross, W. Cresswell, G.D. Werner, B. Acar, A. Chesler, L. Barnes, C.P. Sanguinetti, G. Graham, T.A. Sottoriva, A. (2020). Subclonal reconstruction of tumors by using machine learning and population genetics. Nature genetics, Vol.52 (9), pp. 898-907.  show abstract

Loupakis, F. Depetris, I. Biason, P. Intini, R. Prete, A.A. Leone, F. Lombardi, P. Filippi, R. Spallanzani, A. Cascinu, S. Bonetti, L.R. Maddalena, G. Valeri, N. Sottoriva, A. Zapata, L. Salmaso, R. Munari, G. Rugge, M. Dei Tos, A.P. Golovato, J. Sanborn, J.Z. Nguyen, A. Schirripa, M. Zagonel, V. Lonardi, S. Fassan, M. (2020). Prediction of Benefit from Checkpoint Inhibitors in Mismatch Repair Deficient Metastatic Colorectal Cancer: Role of Tumor Infiltrating Lymphocytes. Oncologist, Vol.25 (6), pp. 481-487.  show abstract

Lupo, B. Sassi, F. Pinnelli, M. Galimi, F. Zanella, E.R. Vurchio, V. Migliardi, G. Gagliardi, P.A. Puliafito, A. Manganaro, D. Luraghi, P. Kragh, M. Pedersen, M.W. Horak, I.D. Boccaccio, C. Medico, E. Primo, L. Nichol, D. Spiteri, I. Heide, T. Vatsiou, A. Graham, T.A. Élez, E. Argiles, G. Nuciforo, P. Sottoriva, A. Dienstmann, R. Pasini, D. Grassi, E. Isella, C. Bertotti, A. Trusolino, L. (2020). Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype. Science translational medicine, Vol.12 (555).  show abstract

Lakatos, E. Williams, M.J. Schenck, R.O. Cross, W.C. Househam, J. Zapata, L. Werner, B. Gatenbee, C. Robertson-Tessi, M. Barnes, C.P. Anderson, A.R. Sottoriva, A. Graham, T.A. (2020). Evolutionary dynamics of neoantigens in growing tumors. Nature genetics, Vol.52 (10), pp. 1057-1066.  show abstract

Smyth, E.C. Vlachogiannis, G. Hedayat, S. Harbery, A. Hulkki-Wilson, S. Salati, M. Kouvelakis, K. Fernandez-Mateos, J. Cresswell, G.D. Fontana, E. Seidlitz, T. Peckitt, C. Hahne, J.C. Lampis, A. Begum, R. Watkins, D. Rao, S. Starling, N. Waddell, T. Okines, A. Crosby, T. Mansoor, W. Wadsley, J. Middleton, G. Fassan, M. Wotherspoon, A. Braconi, C. Chau, I. Vivanco, I. Sottoriva, A. Stange, D.E. Cunningham, D. Valeri, N. (2020). EGFR amplification and outcome in a randomised phase III trial of chemotherapy alone or chemotherapy plus panitumumab for advanced gastro-oesophageal cancers. Gut, .  show abstract

Caravagna, G. Sanguinetti, G. Graham, T.A. Sottoriva, A. (2020). The MOBSTER R package for tumour subclonal deconvolution from bulk DNA whole-genome sequencing data. Bmc bioinformatics, Vol.21 (1), pp. 531-?.  show abstract

Acar, A. Nichol, D. Fernandez-Mateos, J. Cresswell, G.D. Barozzi, I. Hong, S.P. Trahearn, N. Spiteri, I. Stubbs, M. Burke, R. Stewart, A. Caravagna, G. Werner, B. Vlachogiannis, G. Maley, C.C. Magnani, L. Valeri, N. Banerji, U. Sottoriva, A. (2020). Exploiting evolutionary steering to induce collateral drug sensitivity in cancer. Nature communications, Vol.11 (1), pp. 1923-?.  show abstract

Werner, B. Case, J. Williams, M.J. Chkhaidze, K. Temko, D. Fernández-Mateos, J. Cresswell, G.D. Nichol, D. Cross, W. Spiteri, I. Huang, W. Tomlinson, I.P. Barnes, C.P. Graham, T.A. Sottoriva, A. (2020). Measuring single cell divisions in human tissues from multi-region sequencing data. Nature communications, Vol.11 (1), pp. 1035-?.  show abstract

Cresswell, G.D. Nichol, D. Spiteri, I. Tari, H. Zapata, L. Heide, T. Maley, C.C. Magnani, L. Schiavon, G. Ashworth, A. Barry, P. Sottoriva, A. (2020). Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking. Nature communications, Vol.11 (1), pp. 1446-?.  show abstract

Williams, M.J. Zapata, L. Werner, B. Barnes, C.P. Sottoriva, A. Graham, T.A. (2020). Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios. Elife, Vol.9.  show abstract

Spiteri, I. Caravagna, G. Cresswell, G.D. Vatsiou, A. Nichol, D. Acar, A. Ermini, L. Chkhaidze, K. Werner, B. Mair, R. Brognaro, E. Verhaak, R.G. Sanguinetti, G. Piccirillo, S.G. Watts, C. Sottoriva, A. (2019). Evolutionary dynamics of residual disease in human glioblastoma. Ann oncol, Vol.30 (3), pp. 456-463.  show abstract

Turajlic, S. Sottoriva, A. Graham, T. Swanton, C. (2019). Resolving genetic heterogeneity in cancer. Nat rev genet, Vol.20 (7), pp. 404-416.  show abstract

Chkhaidze, K. Heide, T. Werner, B. Williams, M.J. Huang, W. Caravagna, G. Graham, T.A. Sottoriva, A. (2019). Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data. Plos comput biol, Vol.15 (7), p. e1007243.  show abstract

Nawaz, S. Trahearn, N.A. Heindl, A. Banerjee, S. Maley, C.C. Sottoriva, A. Yuan, Y. (2019). Analysis of tumour ecological balance reveals resource-dependent adaptive strategies of ovarian cancer. Ebiomedicine, Vol.48, pp. 224-235.  show abstract

Williams, M.J. Sottoriva, A. Graham, T.A. (2019). Measuring Clonal Evolution in Cancer with Genomics. Annu rev genomics hum genet, Vol.20, pp. 309-329.  show abstract

Williams, M.J. Werner, B. Barnes, C.P. Graham, T.A. Sottoriva, A. (2018). Reply: Is the evolution of tumors Darwinian or non-Darwinian?. National science review, Vol.5 (1), pp. 17-19.

Sottoriva, A. (2018). Divergent adaptation in thyroid cancers. Ann oncol, Vol.29 (6), pp. 1353-1353.

Barry, P. Vatsiou, A. Spiteri, I. Nichol, D. Cresswell, G.D. Acar, A. Trahearn, N. Hrebien, S. Garcia-Murillas, I. Chkhaidze, K. Ermini, L. Huntingford, I.S. Cottom, H. Zabaglo, L. Koelble, K. Khalique, S. Rusby, J.E. Muscara, F. Dowsett, M. Maley, C.C. Natrajan, R. Yuan, Y. Schiavon, G. Turner, N. Sottoriva, A. (2018). The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer. Clin cancer res, Vol.24 (19), pp. 4763-4770.  show abstract

Williams, M.J. Werner, B. Heide, T. Curtis, C. Barnes, C.P. Sottoriva, A. Graham, T.A. (2018). Quantification of subclonal selection in cancer from bulk sequencing data. Nat genet, Vol.50 (6), pp. 895-903.  show abstract

Werner, B. Sottoriva, A. (2018). Variation of mutational burden in healthy human tissues suggests non-random strand segregation and allows measuring somatic mutation rates. Plos comput biol, Vol.14 (6), p. e1006233.  show abstract

Caravagna, G. Giarratano, Y. Ramazzotti, D. Tomlinson, I. Graham, T.A. Sanguinetti, G. Sottoriva, A. (2018). Detecting repeated cancer evolution from multi-region tumor sequencing data. Nat methods, Vol.15 (9), pp. 707-714.  show abstract

Khan, K.H. Cunningham, D. Werner, B. Vlachogiannis, G. Spiteri, I. Heide, T. Mateos, J.F. Vatsiou, A. Lampis, A. Damavandi, M.D. Lote, H. Huntingford, I.S. Hedayat, S. Chau, I. Tunariu, N. Mentrasti, G. Trevisani, F. Rao, S. Anandappa, G. Watkins, D. Starling, N. Thomas, J. Peckitt, C. Khan, N. Rugge, M. Begum, R. Hezelova, B. Bryant, A. Jones, T. Proszek, P. Fassan, M. Hahne, J.C. Hubank, M. Braconi, C. Sottoriva, A. Valeri, N. (2018). Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial. Cancer discov, Vol.8 (10), pp. 1270-1285.  show abstract

Cross, W. Kovac, M. Mustonen, V. Temko, D. Davis, H. Baker, A.-. Biswas, S. Arnold, R. Chegwidden, L. Gatenbee, C. Anderson, A.R. Koelzer, V.H. Martinez, P. Jiang, X. Domingo, E. Woodcock, D.J. Feng, Y. Kovacova, M. Maughan, T. S:CORT Consortium, Jansen, M. Rodriguez-Justo, M. Ashraf, S. Guy, R. Cunningham, C. East, J.E. Wedge, D.C. Wang, L.M. Palles, C. Heinimann, K. Sottoriva, A. Leedham, S.J. Graham, T.A. Tomlinson, I.P. (2018). The evolutionary landscape of colorectal tumorigenesis. Nature ecology & evolution, Vol.2 (10), pp. 1661-1672.  show abstract

Heide, T. Zapata, L. Williams, M.J. Werner, B. Caravagna, G. Barnes, C.P. Graham, T.A. Sottoriva, A. (2018). Reply to 'Neutral tumor evolution?'. Nat genet, Vol.50 (12), pp. 1633-1637.

Vlachogiannis, G. Hedayat, S. Vatsiou, A. Jamin, Y. Fernández-Mateos, J. Khan, K. Lampis, A. Eason, K. Huntingford, I. Burke, R. Rata, M. Koh, D.-. Tunariu, N. Collins, D. Hulkki-Wilson, S. Ragulan, C. Spiteri, I. Moorcraft, S.Y. Chau, I. Rao, S. Watkins, D. Fotiadis, N. Bali, M. Darvish-Damavandi, M. Lote, H. Eltahir, Z. Smyth, E.C. Begum, R. Clarke, P.A. Hahne, J.C. Dowsett, M. de Bono, J. Workman, P. Sadanandam, A. Fassan, M. Sansom, O.J. Eccles, S. Starling, N. Braconi, C. Sottoriva, A. Robinson, S.P. Cunningham, D. Valeri, N. (2018). Patient-derived organoids model treatment response of metastatic gastrointestinal cancers. Science, Vol.359 (6378), pp. 920-926.  show abstract

Heindl, A. Khan, A.M. Rodrigues, D.N. Eason, K. Sadanandam, A. Orbegoso, C. Punta, M. Sottoriva, A. Lise, S. Banerjee, S. Yuan, Y. (2018). Microenvironmental niche divergence shapes BRCA1-dysregulated ovarian cancer morphological plasticity. Nature communications, Vol.9 (1), pp. 3917-?.  show abstract

Lote, H. Spiteri, I. Ermini, L. Vatsiou, A. Roy, A. McDonald, A. Maka, N. Balsitis, M. Bose, N. Simbolo, M. Mafficini, A. Lampis, A. Hahne, J.C. Trevisani, F. Eltahir, Z. Mentrasti, G. Findlay, C. Kalkman, E.A. Punta, M. Werner, B. Lise, S. Aktipis, A. Maley, C. Greaves, M. Braconi, C. White, J. Fassan, M. Scarpa, A. Sottoriva, A. Valeri, N. (2017). Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer. Ann oncol, Vol.28 (6), pp. 1243-1249.  show abstract

Graham, T.A. Sottoriva, A. (2017). Measuring cancer evolution from the genome. The journal of pathology, Vol.241 (2), pp. 183-191.  show abstract

Sottoriva, A. Barnes, C.P. Graham, T.A. (2017). Catch my drift? Making sense of genomic intra-tumour heterogeneity. Biochimica et biophysica acta. reviews on cancer, Vol.1867 (2), pp. 95-100.  show abstract

Sun, R. Hu, Z. Sottoriva, A. Graham, T.A. Harpak, A. Ma, Z. Fischer, J.M. Shibata, D. Curtis, C. (2017). Between-region genetic divergence reflects the mode and tempo of tumor evolution. Nat genet, Vol.49 (7), pp. 1015-1024.  show abstract

Baker, A.-. Huang, W. Wang, X.-. Jansen, M. Ma, X.-. Kim, J. Anderson, C.M. Wu, X. Pan, L. Su, N. Luo, Y. Domingo, E. Heide, T. Sottoriva, A. Lewis, A. Beggs, A.D. Wright, N.A. Rodriguez-Justo, M. Park, E. Tomlinson, I. Graham, T.A. (2017). Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution. Nature communications, Vol.8 (1), pp. 1998-?.  show abstract

Maley, C.C. Aktipis, A. Graham, T.A. Sottoriva, A. Boddy, A.M. Janiszewska, M. Silva, A.S. Gerlinger, M. Yuan, Y. Pienta, K.J. Anderson, K.S. Gatenby, R. Swanton, C. Posada, D. Wu, C.-. Schiffman, J.D. Hwang, E.S. Polyak, K. Anderson, A.R. Brown, J.S. Greaves, M. Shibata, D. (2017). Classifying the evolutionary and ecological features of neoplasms. Nat rev cancer, Vol.17 (10), pp. 605-619.  show abstract

Werner, B. Traulsen, A. Sottoriva, A. Dingli, D. (2017). Detecting truly clonal alterations from multi-region profiling of tumours. Sci rep, Vol.7, p. 44991.  show abstract

Werner, B. Scott, J.G. Sottoriva, A. Anderson, A.R. Traulsen, A. Altrock, P.M. (2016). The Cancer Stem Cell Fraction in Hierarchically Organized Tumors Can Be Estimated Using Mathematical Modeling and Patient-Specific Treatment Trajectories. Cancer research, Vol.76 (7), pp. 1705-1713.  show abstract

Williams, M.J. Werner, B. Barnes, C.P. Graham, T.A. Sottoriva, A. (2016). Identification of neutral tumor evolution across cancer types. Nature genetics, Vol.48 (3), pp. 238-244.  show abstract

Williams, M.J. Werner, B. Graham, T.A. Sottoriva, A. (2016). Functional versus non-functional intratumor heterogeneity in cancer. Molecular & cellular oncology, Vol.3 (4), pp. e1162897-?.  show abstract

Eskilsson, E. Rosland, G.V. Talasila, K.M. Knappskog, S. Keunen, O. Sottoriva, A. Foerster, S. Solecki, G. Taxt, T. Jirik, R. Fritah, S. Harter, P.N. Välk, K. Al Hossain, J. Joseph, J.V. Jahedi, R. Saed, H.S. Piccirillo, S.G. Spiteri, I. Leiss, L. Euskirchen, P. Graziani, G. Daubon, T. Lund-Johansen, M. Enger, P.Ø. Winkler, F. Ritter, C.A. Niclou, S.P. Watts, C. Bjerkvig, R. Miletic, H. (2016). EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation. Neuro-oncology, Vol.18 (12), pp. 1644-1655.

Lipinski, K.A. Barber, L.J. Davies, M.N. Ashenden, M. Sottoriva, A. Gerlinger, M. (2016). Cancer Evolution and the Limits of Predictability in Precision Cancer Medicine. Trends in cancer, Vol.2 (1), pp. 49-63.  show abstract

Piccirillo, S.G. Spiteri, I. Sottoriva, A. Touloumis, A. Ber, S. Price, S.J. Heywood, R. Francis, N.-. Howarth, K.D. Collins, V.P. Venkitaraman, A.R. Curtis, C. Marioni, J.C. Tavaré, S. Watts, C. (2015). Contributions to drug resistance in glioblastoma derived from malignant cells in the sub-ependymal zone. Cancer res, Vol.75 (1), pp. 194-202.  show abstract

Sottoriva, A. Kang, H. Ma, Z. Graham, T.A. Salomon, M.P. Zhao, J. Marjoram, P. Siegmund, K. Press, M.F. Shibata, D. Curtis, C. (2015). A Big Bang model of human colorectal tumor growth. Nat genet, Vol.47 (3), pp. 209-216.  show abstract

Gubernator, M. Slater, S.C. Spencer, H.L. Spiteri, I. Sottoriva, A. Riu, F. Rowlinson, J. Avolio, E. Katare, R. Mangialardi, G. Oikawa, A. Reni, C. Campagnolo, P. Spinetti, G. Touloumis, A. Tavaré, S. Prandi, F. Pesce, M. Hofner, M. Klemens, V. Emanueli, C. Angelini, G. Madeddu, P. (2015). Epigenetic profile of human adventitial progenitor cells correlates with therapeutic outcomes in a mouse model of limb ischemia. Arterioscler thromb vasc biol, Vol.35 (3), pp. 675-688.  show abstract

Piccirillo, S.G. Sottoriva, A. Watts, C. (2015). The role of sub-ventricular zone in gliomagenesis. Aging (albany ny), Vol.7 (10), pp. 738-739.

Kang, H. Salomon, M.P. Sottoriva, A. Zhao, J. Toy, M. Press, M.F. Curtis, C. Marjoram, P. Siegmund, K. Shibata, D. (2015). Many private mutations originate from the first few divisions of a human colorectal adenoma. The journal of pathology, Vol.237 (3), pp. 355-362.  show abstract

Ellis, H.P. Greenslade, M. Powell, B. Spiteri, I. Sottoriva, A. Kurian, K.M. (2015). Current Challenges in Glioblastoma: Intratumour Heterogeneity, Residual Disease, and Models to Predict Disease Recurrence. Front oncol, Vol.5, p. 251.  show abstract

Sottoriva, A. Spiteri, I. Shibata, D. Curtis, C. Tavaré, S. (2013). Single-molecule genomic data delineate patient-specific tumor profiles and cancer stem cell organization. Cancer res, Vol.73 (1), pp. 41-49.  show abstract

Sottoriva, A. Spiteri, I. Piccirillo, S.G. Touloumis, A. Collins, V.P. Marioni, J.C. Curtis, C. Watts, C. Tavaré, S. (2013). Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics. Proc natl acad sci u s a, Vol.110 (10), pp. 4009-4014.  show abstract

Dvinge, H. Git, A. Gräf, S. Salmon-Divon, M. Curtis, C. Sottoriva, A. Zhao, Y. Hirst, M. Armisen, J. Miska, E.A. Chin, S.-. Provenzano, E. Turashvili, G. Green, A. Ellis, I. Aparicio, S. Caldas, C. (2013). The shaping and functional consequences of the microRNA landscape in breast cancer. Nature, Vol.497 (7449), pp. 378-382.  show abstract

Vermeulen, L. Morrissey, E. van der Heijden, M. Nicholson, A.M. Sottoriva, A. Buczacki, S. Kemp, R. Tavaré, S. Winton, D.J. (2013). Defining stem cell dynamics in models of intestinal tumor initiation. Science, Vol.342 (6161), pp. 995-998.  show abstract

Ageron, M. Aguilar, J.A. Al Samarai, I. Albert, A. Ameli, F. André, M. Anghinolfi, M. Anton, G. Anvar, S. Ardid, M. Arnaud, K. Aslanides, E. Assis Jesus, A.C. Astraatmadja, T. Aubert, J.-. Auer, R. Barbarito, E. Baret, B. Basa, S. Bazzotti, M. Becherini, Y. Beltramelli, J. Bersani, A. Bertin, V. Beurthey, S. Biagi, S. Bigongiari, C. Billault, M. Blaes, R. Bogazzi, C. de Botton, N. Bou-Cabo, M. Boudahef, B. Bouwhuis, M.C. Brown, A.M. Brunner, J. Busto, J. Caillat, L. Calzas, A. Camarena, F. Capone, A. Caponetto, L. Cârloganu, C. Carminati, G. Carmona, E. Carr, J. Carton, P.H. Cassano, B. Castorina, E. Cecchini, S. Ceres, A. Chaleil, T. Charvis, P. Chauchot, P. Chiarusi, T. Circella, M. Compère, C. Coniglione, R. Coppolani, X. Cosquer, A. Costantini, H. Cottini, N. Coyle, P. Cuneo, S. Curtil, C. D Amato, C. Damy, G. van Dantzig, R. De Bonis, G. Decock, G. Decowski, M.P. Dekeyser, I. Delagnes, E. Desages-Ardellier, F. Deschamps, A. Destelle, J.-. Di Maria, F. Dinkespiler, B. Distefano, C. Dominique, J.-. Donzaud, C. Dornic, D. Dorosti, Q. Drogou, J.-. Drouhin, D. Druillole, F. Durand, D. Durand, R. Eberl, T. Emanuele, U. Engelen, J.J. Ernenwein, J.-. Escoffier, S. Falchini, E. Favard, S. Fehr, F. Feinstein, F. Ferri, M. Ferry, S. Fiorello, C. Flaminio, V. Folger, F. Fritsch, U. Fuda, J.-. Galatá, S. Galeotti, S. Gay, P. Gensolen, F. Giacomelli, G. Gojak, C. Gómez-González, J.P. Goret, P. Graf, K. Guillard, G. Halladjian, G. Hallewell, G. van Haren, H. Hartmann, B. Heijboer, A.J. Heine, E. Hello, Y. Henry, S. Hernández-Rey, J.J. Herold, B. Hößl, J. Hogenbirk, J. Hsu, C.C. Hubbard, J.R. Jaquet, M. Jaspers, M. de Jong, M. Jourde, D. Kadler, M. Kalantar-Nayestanaki, N. Kalekin, O. Kappes, A. Karg, T. Karkar, S. Karolak, M. Katz, U. Keller, P. Kestener, P. Kok, E. Kok, H. Kooijman, P. Kopper, C. Kouchner, A. Kretschmer, W. Kruijer, A. Kuch, S. Kulikovskiy, V. Lachartre, D. Lafoux, H. Lagier, P. Lahmann, R. Lahonde-Hamdoun, C. Lamare, P. Lambard, G. Languillat, J.-. Larosa, G. Lavalle, J. Le Guen, Y. Le Provost, H. LeVanSuu, A. Lefèvre, D. Legou, T. Lelaizant, G. Lévéque, C. Lim, G. Lo Presti, D. Loehner, H. Loucatos, S. Louis, F. Lucarelli, F. Lyashuk, V. Magnier, P. Mangano, S. Marcel, A. Marcelin, M. Margiotta, A. Martinez-Mora, J.A. Masullo, R. Mazéas, F. Mazure, A. Meli, A. Melissas, M. Migneco, E. Mongelli, M. Montaruli, T. Morganti, M. Moscoso, L. Motz, H. Musumeci, M. Naumann, C. Naumann-Godo, M. Neff, M. Niess, V. Nooren, G.J. Oberski, J.E. Olivetto, C. Palanque-Delabrouille, N. Palioselitis, D. Papaleo, R. Păvălaş, G.E. Payet, K. Payre, P. Peek, H. Petrovic, J. Piattelli, P. Picot-Clemente, N. Picq, C. Piret, Y. Poinsignon, J. Popa, V. Pradier, T. Presani, E. Prono, G. Racca, C. Raia, G. van Randwijk, J. Real, D. Reed, C. Réthoré, F. Rewiersma, P. Riccobene, G. Richardt, C. Richter, R. Ricol, J.S. Rigaud, V. Roca, V. Roensch, K. Rolin, J.-. Rostovtsev, A. Rottura, A. Roux, J. Rujoiu, M. Ruppi, M. Russo, G.V. Salesa, F. Salomon, K. Sapienza, P. Schmitt, F. Schöck, F. Schuller, J.-. Schüssler, F. Sciliberto, D. Shanidze, R. Shirokov, E. Simeone, F. Sottoriva, A. Spies, A. Spona, T. Spurio, M. Steijger, J.J. Stolarczyk, T. Streeb, K. Sulak, L. Taiuti, M. Tamburini, C. Tao, C. Tasca, L. Terreni, G. Tezier, D. Toscano, S. Urbano, F. Valdy, P. Vallage, B. Van Elewyck, V. Vannoni, G. Vecchi, M. Venekamp, G. Verlaat, B. Vernin, P. Virique, E. de Vries, G. van Wijk, R. Wijnker, G. Wobbe, G. de Wolf, E. Yakovenko, Y. Yepes, H. Zaborov, D. Zaccone, H. Zornoza, J.D. Zúñiga, J. (2011). ANTARES: The first undersea neutrino telescope. Nuclear instruments and methods in physics research section a: accelerators, spectrometers, detectors and associated equipment, Vol.656, pp. 11-38.  show abstract

Sottoriva, A. Vermeulen, L. Tavaré, S. (2011). Modeling Evolutionary Dynamics of Epigenetic Mutations in Hierarchically Organized Tumors. Plos comput. biol., Vol.7.

Sottoriva, A. Verhoeff, J.J. Borovski, T. McWeeney, S.K. Naumov, L. Medema, J.P. Sloot, P.M. Vermeulen, L. (2010). Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity. Cancer res, Vol.70 (1), pp. 46-56.  show abstract

Sottoriva, A. Sloot, P.M. Medema, J.P. Vermeulen, L. (2010). Exploring cancer stem cell niche directed tumor growth. Cell cycle, Vol.9 (8), pp. 1472-1479.  show abstract

Sottoriva, A. Tavaré, S. (2010). Integrating approximate Bayesian computation with complex agent-based models for cancer research. Compstat 2010 - proceedings in computational statistics, eds. saporta g & lechevallier y. springer, physica verlag, , pp. 57-66.

Portegies Zwart, S. McMillan, S. Harfst, S. Groen, D. Fujii, M. Nualláin, B.Ó. Glebbeek, E. Heggie, D. Lombardi, J. Hut, P. Angelou, V. Banerjee, S. Belkus, H. Fragos, T. Fregeau, J. Gaburov, E. Izzard, R. Jurić, M. Justham, S. Sottoriva, A. Teuben, P. van Bever, J. Yaron, O. Zemp, M. (2009). A multiphysics and multiscale software environment for modeling astrophysical systems. New astronomy, Vol.14, pp. 369-378.  show abstract

Bollen, Y. Stelloo, E. van Leenen, P. van den Bos, M. Ponsioen, B. Lu, B. van Roosmalen, M.J. Bolhaqueiro, A.C. Kimberley, C. Mossner, M. Cross, W.C. Besselink, N.J. van der Roest, B. Boymans, S. Oost, K.C. de Vries, S.G. Rehmann, H. Cuppen, E. Lens, S.M. Kops, G.J. Kloosterman, W.P. Terstappen, L.W. Barnes, C.P. Sottoriva, A. Graham, T.A. Snippert, H.J. Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns. Nature genetics, Vol.53 (8), pp. 1187-1195.  show abstract

Graham, T. Heide, T. Househam, J. Cresswell, G. Spiteri, I. Lynn, C. Mossner, M. Kimberley, C. Fernandez-Mateos, J. Chen, B. Zapata, L. James, C. Barozzi, I. Chkhaidze, K. Nichol, D. Berner, A. Schmidt, M. Lakatos, E. Baker, A.-. Costa, H. Mitchinson, M. Jansen, M. Caravagna, G. Ramazzotti, D. Shibata, D. Bridgewater, J. Rodriguez-Justo, M. Magnani, L. Sottoriva, A. The co-evolution of the genome and epigenome in colorectal cancer. Biorxiv, .