Professor Céire Costelloe is a Medical Statistician with experience in building and leading research teams using real world healthcare data to improve health service delivery and patient outcomes.
She is trained in Medical Statistics and Immunology. She obtained her PhD in Immunology from Trinity College, Dublin. She undertook a postdoctoral research post at the UKCRC Clinical Trials unit at the University of Bristol during which time she secured a NIHR training fellowship to allow her to undertaken a MSc in Medical Statistics at the London School of Hygiene and Tropical Medicine.
She was awarded a NIHR postdoctoral fellowship in 2009 which focussed on the examination of risk factors for the development of antimicrobial resistant (AMR) infection, using real world healthcare data. This led to a highly cited BMJ publication reporting, for the first time, the association between antibiotic use and the risk of AMR at an individual patient level. This research led to changes in UK and EU guidelines on antibiotic use in primary care.
After moving to Imperial College London to take up a newly establish NIHR Health Protection research unit in AMR Céire was awarded a NIHR Career Development Fellowship to develop her research group focussing on the use of real-world healthcare data for the evaluation of interventions targeting AMR. She was Director of the newly established Global Digital health from 2018-2021.
She has a keen interest in pragmatic clinical trial design and natural experiments, and how novel statistical methodology can improve the robustness of evaluations using observational data. She is a Chartered Statistician and has spent time working the UKCRC Bristol Randomised Trials Collaboration, as well as holding a Lectureship in Medical Statistics within the UKCRC Pragmatic Clinical Trials unit at Queen Mary university. She maintain close collaboration with Imperial College London and is a Visiting Professor in Digital health and Medical Statistics.